Small molecules that promote neurogenesis in vitro. Rishton, G.M. Recent Patents on CNS Drug Discovery (2008) in press. http://www.bentham.org/rpcn/Pre-Preview.htm#top
A Bioreactor System Based on a Novel Oxygen Transfer Method. Qian Jia, Huicheng Li, Mizhou Hui, Ni Hui, Aziz Joudi, Gilbert Rishton, Lei Bao, Ming Shi, Xiuqin Zhang, Li Luanfeng, Jiangyun Xu, and Guoqing Leng. BioProcess International (2008) 6 (6) 66-71. http://www.bioprocessintl.com/default.asp?page=article_display&docid=60120088&rtn=ci
Natural Products as a Robust Source of New Drugs and Drug Leads: Past Successes and Present Day Issues. Rishton, G.M. American Journal of Cardiology (2008) 101:43D-49D. http://linkinghub.elsevier.com/retrieve/pii/S0002914908002178
Aggregator compounds confound amyloid fibrillization assay. Gilbert M. Rishton Nat Chem Biol. (2008) 4 (3):159-160. http://www.nature.com/nchembio/journal/v4/n3/fig_tab/nchembio0308-159_F1.html
Molecular diversity in the context of leadlikeness: Compound properties that enable effective biochemical screening. Rishton, G. M. Current Opinion in Chemical Biology (2008) 12:340-351. http://www.ncbi.nlm.nih.gov/pubmed/18328272
Inhibitors of cognitive decline. Rishton, G.M.; Arai, H.; Kai, Z.; Fullenwider, C.; Beierle, K. Full Utility. Pat. Appl. (WO/2008/042755). http://www.wipo.int/pctdb/en/wo.jsp?WO=2008042755
Unnatural β-secretase inhibitors derived from the conditioned extraction of ginger root. Rishton, G.M.; Arai, H.; Kai, Z.; Fullenwider, C.; Beierle, K. Prov. Pat. Appl.2006, 17069.
Computational approaches to the prediction of blood-brain barrier permeability: A comparative analysis of central nervous system drugs versus secretase inhibitors for Alzheimer's disease. GM Rishton, K LaBonte, AJ Williams, K Kassam, E Kolovanov. Current Opinion in Drug Discovery and Development (2006) 9:303-313. http://www.ncbi.nlm.nih.gov/pubmed/16729726
Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations. Gilbert M. Rishton. Invited Review: Medicinal Chemistry (2005) 1 (5), 519-527. http://www.ingentaconnect.com/content/ben/mc/2005/00000001/00000005/art00011
Nonleadlikeness and Leadlikeness in Biochemical Screening. Gilbert M. Rishton (Invited Review): Drug Discovery Today (2003) 8(2) 86-96. http://www.ncbi.nlm.nih.gov/pubmed/12565011
Fenchylamine Sulfonamide Inhibitors of Amyloid β Production by the γ-Secretase Proteolytic Pathway: Potential Small Molecule Therapeutic Agents for the Treatment of Alzheimer’s Disease. Gilbert M. Rishton, Daniel M. Retz, Paul A. Tempest, James Novotny, Steve Kahn, James J. S. Treanor, Jack D. Lile, and Martin Citron: Journal of Medicinal Chemistry (2000) 43(12), 2297-2299. http://cat.inist.fr/?aModele=afficheN&cpsidt=1407737
Reactive Compounds and in vitro False Positives in HTS. Gilbert M. Rishton (Invited Editorial): Drug Discovery Today (1997) 2(9) 382-384. http://www.ingentaconnect.com/content/els/13596446/1997/00000002/00000009/art01083
Human neural stem cell differentiation and the effects of some small molecule drugs and dietary antioxidants. Gilbert M. Rishton, Emily Mazzucchi, Kenneth Diffenderfer, Sidney Pehrson, Yue Jia Wu, Ching-Hua Wang. The Channel Islands Alzheimer’s Institute and Department of Biology, California State University, Channel Islands , One University Drive, Camarillo, CA 93012. ACS Western Regional Meeting, September 2008. http://acs.confex.com/acs/wrm08/techprogram/P61858.HTM
The Design and Synthesis of Curcumin Analogues to Inhibit beta-Secretase. Gilbert M. Rishton, Philip D. Hampton, Blake Gillespie, Andrew Merithew, Justin Hilf, and Andrew Yaeger. Alzheimer's Institute, California State University Channel Islands, Camarillo, CA, California State University Channel Islands, Camarillo, CA 92012. ACS Western Regional Meeting, September 2008. http://acs.confex.com/acs/wrm08/techprogram/P61933.HTM
Chemically Conditioned Extracts of Ginger Oil: Leadlike “Alkaloidal” Compounds Derived from Natural Extracts via Reductive Amination. Hiromi Arai, Kristin Beierle, Cody Fullenwider, Zoya Kai, Gilbert M. Rishton: Poster presentation for American Chemical Society Western Regional Meeting (January 22-25, 2006) Anaheim, CA.
Chemically Conditioned Extracts of Ginger Oil: Leadlike “Alkaloidal” Compounds Derived from Natural Extracts via Reductive Amination. Hiromi Arai, Kristin Beierle, Cody Fullenwider, Zoya Kai, Gilbert M. Rishton: Poster presentation for 18th Annual Biotechnology Symposium: The Brain and the Future (January 13-15, 2006) San Jose, CA.
Chemically Conditioned Extracts of Ginger Oil: Leadlike Compounds Derived from Natural Extracts for Biochemical Screening. Hiromi Arai, Zoya Kai, Gilbert M. Rishton: Poster presentation for Annual Biomedical Research Conference for Minority Students (November 2-5, 2005) Atlanta, GA.
Nonleadlikeness, Leadlikeness, and Target Tractability in Small Molecule Drug Discovery. Gilbert M. Rishton: Oral presentation for Molecules that Matter: Case Studies in Medicinal Chemistry. (April 12, 2005) Berlin, Germany.
